Nasolabial folds are the lines that run from the sides of our nose to the corners of our mouth. As we age, they tend to become increasingly noticeable. Nasolabial fold fillers from Restylane® helps you achieve a more youthful appearance. 1-3
Nasolabial fold fillers from Restylane® are hyaluronic acid based injectables that are used to reduce nasolabial folds,
for a refreshed appearance. Restylane® fillers are unique since they are clinically proven to make you look natural when
your face is at rest as well as when you make facial expressions.1-3 Take a look at what these fillers for nasolabial folds can do.
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Restylane® DEFYNE™ helps define the natural contours of the
midface.1-3,11 It’s moderately soft to provide support when correcting
wrinkles around the mouth but also flexible.4-6 It will follow your facial expressions in sync with your skin for natural-looking results.1-3
Restylane® DEFYNE™ gives you up to 12 months of aesthetic improvement
when treating nasolabial folds, with clinically proven naturalness.9
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Get support exactly where you need it. Restylane® is a firm filler4 used to support and create projection.7,12,13 It can for example be used to treat deeper wrinkles and folds. Restylane® is the original hyaluronic acid dermal filler*14,15 with more than 27 years of experience.16,17†
Restylane® is a natural choice, with a composition very close to natural hyaluronic acid in the skin.15,18
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Speak with a healthcare practitioner about treating nasolabial
folds and other wrinkles around the mouth.
References
* Restylane® LYFT™ is the firmest (highest G’) NASHA® gel and has a higher G’ (elastic modulus) than HA fillers in the Juvéderm, Belotero, and Teosyal product ranges.2–4 1. Coleman S R et al. Aesthetic Surgery Journal vol. 26,1S (2006): S4-9. 2. Galderma. Data on file. MA-43049. xStrain and G’ (Global). 3. Galderma. Data on file. MA-34483. xStrain and G’ (US).4. Öhrlund A et al. J Drugs Dermatol. 2024;23(1):1332–6.5. Rogerio V et al. J Stomatol Oral Maxillofac Surg. 2022;123(4):440–7. 6. Di Gregorio C et al. Clin Cosmet Investig Dermatol. 2022;15:681–90.7. Nikolis A et al. Aesthet Surg J Open Forum. 2020;2(1):ojaa005.8. Lundgren B et al. J Drugs Dermatol. 2018;17(9):982–6.9. Nikolis A et al. Poster presentation: The CHEEKY study: effectiveness of cheek treatment with hyaluronic acid fillers HAVOL and HALYF. Presented at: AMWC, Monte Carlo, Monaco.2022. 10. Marcus K et al. Plast Reconstr Surg. 2022 Dec; 150(6): 1240–1248. 11. Galderma DOF. MA-56724 X-strain and G' including Shaype.12. Nikolis A, et al. J Drugs Dermatol. 2024;23(4):255–61. 13. Restylane® LYFT™ IFU (EU). 14. Huang SH, Tsai TF. J Drugs Dermatol. 2020;19(9):836–42.15. Andriopoulos B et al. Poster presentation: Facial augmentation with hyaluronic acid fillers in an Asian population. Presented at: AMWC, Monte Carlo, Monaco. 2019. 16. Restylane® DEFYNE™ IFU (EU). 17. Percec I et al. Plast Reconstr Surg. 2020;145:295e–305e. 18. Philipp-Dormston WG et al. Dermatol Surg. 2018;44(6):826–32. 19. Solish N et al. J Cosmet Dermatol. 2019;18(3):738–46.
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